Vaping vs. smoking: Long term effects, benefits, and risks Difference Between E Cigarette and Vape Difference Between E Cigarette vs Vape Vaping vs. Smoking: Which One Will Kill You Faster? Dr. Zembroski Vapes might be less harmful than traditional cigarettes and might help smokers quit smoking, but they are not safe, especially for individuals younger than 25 years old. Plus, much is still unknown Which Smoking Habit Puts You Most at Risk?