Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes What is glutathione? Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver. It is essential because it Glutathione Synthesis in Normal Liver and in Yoshida AH 130 Hepatoma Novel Mechanism for Dehalogenation and Glutathione Conjugation of Dihalogenated Anilines in Human Liver Microsomes: Evidence for ipso Glutathione Addition Chemical Research in Toxicology The Liver: Inflammation, Oxidative Stress, and Glutathione Synthesis IMMA Immunity Matters