Melanoma Pictures: Skin Changes and What to Look For Smoker's melanosis Wikipedia Differentiating between early melanomas and melanocytic nevi: A state of the art review ScienceDirect How Can You Tell if It's Melanoma or Just a Mole? Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in