Critical Role of Flavin and Glutathione in Complex IMediated Bioenergetic Failure in Brain Ischemia Reperfusion Injury Stroke Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Transcranial amelioration of inflammation and cell death after brain injury Nature The C718T polymorphism in the 3 untranslated region of glutathione peroxidase 4 gene is a predictor of cerebral stroke in patients with essential hypertension Hypertension Research