This is how laxative abuse affects colon resulting in melanosis coli . Gene expression and hepatitis C virus infection Gut Changes in the epidemiology and distribution of the hepatitis C virus genotypes in North Eastern Spain over the last 35 years Gastroenterologa y Hepatologa Nontargeted hepatitis C virus (HCV) screening was superior to targeted screening for identifying HCV infection in the emergency department. https: ja.ma 44l78hX Melanosis Coli Treatment & Management Point of Care StatPearls